Turn-based strategy · In beta

Hold the barrier.
Protect the lymph node.

A turn-based strategy game played on a cross section of infected tissue. Diapedesis is the process a white blood cell uses to squeeze out of a blood vessel and into tissue — which is how your cells get to the fight.

Android builds go out through the testers group. iPhone testing starts soon — join the same group and you will be told the moment TestFlight opens.

What you are actually doing

The situation

An infection working downward

A virus starts at the epithelial barrier along the top and pushes toward the lymph node at the bottom. You spend ATP recruiting immune cells and move them up through the vessels to meet it.

The catch

Your own cells cost you tissue

You lose if a pathogen reaches the node — or if too much of the barrier is destroyed. A cytotoxic T cell lysing an infected cell stops the burst but still spends that tissue. Clearing an infection is never free.

The payoff

Adaptive immunity is earned

A kill leaves viral debris. A dendritic cell collects it and carries it to the lymph node. Presenting it there unlocks T cells and B cells — and antibody that only binds the variant it was raised on.

Screenshots

The board mid-match: infected barrier cells and immune units in the vessel. Recruiting on the lymph node band with the side panel showing ATP and barrier integrity. Immune cells advancing through the circulatory corridor. A later turn, with adaptive cells in play.

Geography matters

Cells cannot walk anywhere

The lymph node connects to open tissue only through corridors, and each corridor carries particular cells. Neutrophils, macrophages, T cells and B cells ride the bloodstream; the lymphatic vessel carries dendritic cells and macrophages and keeps the virus out. Virus particles use the bloodstream too, which makes the circulatory column the ground worth holding.

Three ways to play it

Vaccinated starts you primed — T and B cells from turn one, and the virus never mutates. Normal is the intended fight. Anti-Vaxxer cuts your metabolic output, speeds up shedding, and lets the virus drift past the antibody you have already raised.

Built for a phone in landscape — and a desktop

Diapedesis runs on iOS and Android, and on macOS with full mouse and keyboard control: scroll to zoom, drag or arrow keys to pan, and a fit control for when you lose the board. Windows and Linux builds are in progress.